![]() ![]() As a consequence, this methodology does not only identify genes playing a dual role (e.g. Eventually, by means of random forests, MoonlightR predicts two specific roles for the candidate driver genes: i) tumor suppressor genes (TSGs) and ii) oncogenes (OCGs). The method first infers gene regulatory networks and then carries out a functional enrichment analysis (FEA) (implementing an upstream regulator analysis, URA) to score the importance of well-known biological processes with respect to the studied cancer type. Results: We present an R/bioconductor package called MoonlightR which returns a list of candidate driver genes for specific cancer types on the basis of TCGA expression data. Motivation: The understanding of cancer mechanism requires the identification of genes playing a role in the development of the pathology and the characterization of their role (notably oncogenes and tumor suppressors). Other than that, great game and good job.DOI: 10.18129/B9.bioc.MoonlightR Identify oncogenes and tumor suppressor genes from omics data The fact that there is no mouse even for the main menu is just a tad odd imo. ![]() It works just fine with just a keyboard, I've just noticed that mouse support would be a nice qol update, especially for navigating the inventory and menues. ![]() I have the game on GoG and have been playing for several hours. ![]() I recognize that this is a special case and you wouldn't make changes for a single player, but I think in general, a lot of pc players might like mouse support, even if the game doesn't necessarily need it. I am away from home for several years and don't have easy access to a controller or a place to buy one unfortunately. It didn's seem necessary to add mouse support only for the main menu - we focused on polishing the keyboard and controller controls.īut we love to hear your feedback - we're collecting it and can always adjust things post-release. Game works perfectly fine with both controller and keyboard. ![]()
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